Differences in cardiac involvement between carriers of Duchenne and Becker muscular dystrophy - a cardiovascular magnetic resonance study
نویسندگان
چکیده
Background Duchenne (DMD) and Becker (BMD) muscular dystrophies are X-linked recessive disorders associated with both skeletal myopathy and progressive cardiomyopathy in males. Although BMD patients present milder skeletal muscle involvement, they have been shown to present more advanced cardiomyopathy than DMD. Female DMD/BMD carriers are usually free of skeletal muscle symptoms but they may also develop cardiomyopathy. The present study aimed at characterizing the presence and pattern of cardiac abnormalities in a group of genetically-proven MD-carriers by means of comprehensive CMR studies. Moreover, we wanted to test whether DMD carriers (DMDc) and BMD carriers (BMDc) are differently affected.
منابع مشابه
Interval from the onset of transmitral flow to annular velocity is a marker of LV filling pressure.
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